VSL® Probiotics: A Legacy of Science in Every Strain.

Building on the trusted heritage of VSL#3®, VSL®Probiotics now includes innovative supplements like VSL4®, designed for everyday wellness.

  • Trusted worldwideA legacy built on trust and expertise.

  • Rooted in scienceGuided by probiotic research.

  • Commitment to qualityEnsuring potency and reliability.

  • Designed for diverse needsSupporting gut and women’s health.

    A Gold Standard in Probiotics

    • A powerful probiotic medical food
    • The #1 gastroenterologist-recommended multi-strain probiotics brand
    • Ultra-high-potency — guaranteed through expiration when stored as recommended.
    • 8 complementary probiotic strains from 3 different genera.
    • Used in clinical practice and supported by clinical and scientific research.
    SHOP NOW

    Science Over Hype.Purpose Over Promises.

    Built on the legacy of VSL#3®— a probiotic trusted by healthcare professionals and recognized for its scientific rigor — VSL® Probiotics continues to advance microbiome science through targeted, high-quality formulations that support both clinical dietary management and everyday wellness.

    • Committed to Potency

      Potent probiotic formulations guaranteed tomaintain labeled CFU counts throughexpiration.

    • Designed for Viability

      Carefully designed formulations that helpsafeguard live bacteria from production todelivery.

    • Science-Led Strain

      Thoughtfully formulated with complementaryprobiotic strains chosen for function andpurpose.

    • A Legacy of Expertise

      A probiotic heritage recognized for itsconsistency, credibility, and professionaltrust.

      What Our Customers Say

      • Works Great!

        Really calms my Gut. I'm so thankful mydoctor recommended this product! Itworks well everyday

        Carol F.

      • Best Probiotic ever!

        Can't live without it! Keeps my digestivesystem in its lane and I don't have to beon edge all the time about getting sick...

        Awilda G.

      • Best probiotic ever

        My doctor recommended I should useVSL#3 probiotics. It has honestlyimproved my quality of life. It is expensi...

        SHARON R.

      • Wonderful Probbiotic

        This is the only probiotic that works forme!

        Daryl R.

      • Miraculous. Everyone should be on this

        The most amazing probiotic on theplanet. Healed my belly when NOTHINGelse would.

        Kelly F.

      • Works Great!

        Awesome product. worked better thanother probiotics I've tried.

        CarV.

        Clean Ingredients. Trusted Standards.

        We believe what's not in your probiotic is just as important as what is.

        • Dairy-Free

        • Gluten-Free

        • No GMOs

        • Soy-Free

          The VSL® Probiotics Difference

          Pioneers in Probiotics. Leaders in Gut Health.

          VSL#3®is an ultra-high-potency probiotic medical food — and the #1 gastroenterologist-recommended multi-strain probiotics brand.†Developed for people with serious gastrointestinal conditions, it’s trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.

          Built on Science. Proven in Practice.

          Driven by research — not marketing trends — VSL#3®is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.

          Ultra-High Potency. Guaranteed.

          VSL#3®products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3®guarantees potency through expiration when stored as directed.

          Clinically Researched Formulas. Real-World Results.

          Each VSL#3®product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3®family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.

          It’s What’s on the Inside

          Our unique8-strain formulationis designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.

          • Bifidobacterium

            Bifidobacterium breve,Bifidobacteriumlactis (previously classified as B.infantis),Bifidobacterium lactis(previously classified asB. longum)

          • Lactobacillus

            Lactobacillus acidophilus,Lactobacillushelveticus (previously classified as L.delbrueckii subsp. bulgaricus),Lactobacillus paracasei,Lactobacillusplantarum

          • Streptococcus

            Streptococcus thermophilus

            • VSL#3®combines 8

              complementary probiotic strains from 3 different genera to supportgut microbiota diversity and digestive balance.

            • VSL#3® is distributed in over 40

              countries and counting - it's trusted by healthcare professionals andpatients worldwide.

            • VSL#3® is Dairy-Free

              for individuals who avoid dairy due to dietary preferences or
              sensitivities.